Chest pain that feels like angina or a heart attack
Shortness of breath, not relieved by rest
Sudden, severe headache
Sudden, severe abdominal pain
Bright red stools, or bleeding from your bowels
Coughing up bright red blood
Fainting spells
Heart rate faster than 150 beats per minute with shortness of breath, or a new irregular heart rate
Sudden numbness or weakness in arms or legs
An elevated temperature of more than 38°C two times within 24 hours
Extreme fatigue
Pain in your calf that becomes worse when lifting toes towards your head
Acute gout flare-up
Persistent bleeding or ooze from your chest or leg wound
Sharp pain when taking a deep breath
Skin rash
Urinary Tract Infection: burning, frequent urination, urgency or bloody urine
Weight gain of more than 1kg within 24 hours
Worsening ankle swelling or leg pain
Worsening shortness of breath
New onset of nausea, vomiting or diarrhoea